What is the term for the fine grinding of a powder necessary to achieve a more uniform particle size?

The term that refers to the fine grinding of a powder to achieve a more uniform particle size is trituration. This process is essential in pharmacy because uniform particle size can enhance the efficacy and consistency of the medication. Trituration involves grinding a substance to increase its surface area, which can improve its solubility and the rate at which it can be absorbed by the body when administered.

Milling generally refers to a broader processing technique that may not specifically imply the fine grinding necessary for uniformity. Granulation is a different process used to create granules from powders, which is more about forming a new solid rather than refining size. Powdering is a less technical term and does not specifically indicate the controlled fine grinding needed to achieve uniform particle size.

Thus, trituration is the precise term used when discussing the controlled process of grinding to achieve finer and more uniform powders in pharmaceutical applications.